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KMID : 0361619720070040405
Journal of the Korean Orthopaedic Association
1972 Volume.7 No. 4 p.405 ~ p.411
Clinical Study of Steroid Induced Side Effects in Orthopedic Field


Abstract
Clinical study of 40 cases who have used steroid preparations was done during past 6 months from March ¢¥72 to September ¢¥72.
1. The youngest patient was twenty, the oldest seventy-four and the average fifty-two. Eighty per cent was included between from 41 to 70 year of age.
2. And the sex ratio was 1:4.7.
3. Diagnostic incidence was 47.5% in degenerative arthritis and 40% in rheumatoid arthritis.
4. The causes of administration were multiple joint pain (35%), lumbago (27.5%) and pain on knee joint (25%) in order.
5. Prednisolone (60%), dexacortisil (25%) and dexamethasone (12.5%) were used in 97.5 6. The source of steroid was drung store (95%) or doctor (5%).
7. The time from first dose to last dose was less than lmonth (20%), 1-3 month(10%), 4-6 month
(7.5%) and more than 1 year (52.5%). And 3 cases have used for more than 5 years.
8. Eighteen cases (45%) used steroid continuously and 22 cases (55%) irregularly.
9. Transient effectiveness was experienced in 92.5% with steroid. administration, that was one of
the causes of steroid usage without doctor¢¥s prescription. 10. The side effects were as follows; moon face (62.5%), ulcer (20%), fat deposition (15%), oste¡þoporosis (15%), peripheral edema (10%), elevation of blood pressure (7.5%), malar flush(7. 5 % ), vertebral compression fracture (7.5%), obesity (5%), psychotic change (5%), pyogenic arthritis (5%), diabetes (2.5%), sepsis (2.5%), adrenal insufficiency (2.5%), avascular necrosis (2.5%) and stress fracture of femur neck (2.5%).
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